UK scientists have identified a new cause of damage in asthma, revealing that cells lining the airways are squeezed during attacks, leading to destruction. This finding suggests that drugs targeting this process could prevent harm rather than just managing its aftermath. While existing medications can reduce inflammation and keep airways open, repeated attacks can cause permanent scarring and narrowing.
Lead researcher Prof Jody Rosenblatt emphasized the importance of protecting the airway lining, which acts as the body’s first defence against infections. The team is exploring gadolinium as a potential preventive treatment, although further research is required to determine its safety and effectiveness. Asthma and Lung UK highlighted the importance of continuing to use prescribed medications correctly and emphasised the need for new treatments to address the underlying causes of asthma. With over five million people affected by asthma in the UK, early intervention and appropriate medical assistance during attacks are crucial.