Exploring the Crucial Need, Challenges, and Breakthroughs in Autism Research

This video is from a presentation by Caroline, a researcher in the Department of Psychological and Brain Sciences at Dartmouth. Her research focuses on cognitive neuroscience approaches to memory, perception, neurodiversity, and autism.

Why is autism Research is Needed?

  • Lack of understanding about neurobiological causes
  • Autism is a constellation of symptoms; no clear core or cause
  • Prevalence rates and variations across different regions

What are the challenges in Autism Research?

  • Difficulty in early diagnosis (average age of diagnosis is four)
  • No approved drugs targeting core features of autism
  • Lack of understanding of human neurodiversity

Current Autism Research:

  • Studying brain activity, connectivity patterns, and molecular composition
  • Three scales: regional activity, connectivity between regions, molecular composition

Findings from MRI Studies:

  • Differences in motion-sensitive areas of the brain
  • Conflicting findings on connectivity patterns (local vs. global connections)
  • Discovery of specific molecules (GABA) impacting sensory sensitivities in autism

What are the implications of these findings?

  • Potential for early diagnosis using brain signatures
  • Identification of neural pathways for targeted drug therapies
  • Understanding unique neural profiles of individuals with autism

Here is the full lecture: https://www.youtube.com/watch?v=2__A_Mb0V0g&ab_channel=Dartmouth

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