New studies into malnutrition and infant mortality highlight Queen Mary’s close collaboration with researchers in Zimbabwe and Zambia

University courses Medicine & Psychology
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The research papers from Queen Mary’s Blizard Institute, focus on childhood malnutrition in Zambia and Zimbabwe. The Tropical Gastroenterology and Nutrition Group (TROPGAN) in Lusaka and the Zvitambo Institute for Maternal and Child Health Research in Harare aim to understand and treat childhood malnutrition.

The first paper presents findings from the Therapeutic Approaches to Malnutrition Enteropathy (TAME) study, which evaluated treatments for malnutrition enteropathy in children with severe acute malnutrition (SAM). The study found evidence supporting interventions to enhance mucosal membrane healing and reduce gut inflammation, potentially improving outcomes for children affected by SAM.

The second paper uncovers why boys born to mothers with HIV are at greater risk of health problems and death in infancy. The study, led by Dr. Ceri Evans, analyzed outcomes in infants exposed and unexposed to maternal HIV in rural Zimbabwe. It found that infants exposed to maternal HIV had increased risk of immune abnormalities, inflammation, and mortality. Targeting maternal inflammation during pregnancy could potentially reduce infant mortality.

Additionally, HIV-exposed babies, especially boys, showed differences in immune development, potentially making them less effective in dealing with infections.

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It’s amazing to see the efforts being made to address childhood malnutrition , especially considering the significant impact it can have on children’s health and well-being. It’s incredible how such targeted treatments could make a difference in the lives of these children.

As for the second paper, it’s concerning to hear about the increased risk of health problems and mortality among boys born to mothers with HIV in rural Zimbabwe. Dr. Ceri Evans’ research sheds light on the importance of addressing maternal inflammation during pregnancy to potentially reduce infant mortality rates.

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